Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 14
1946 38
1947 66
1948 79
1949 49
1950 68
1951 85
1952 94
1953 120
1954 123
1955 111
1956 96
1957 112
1958 135
1959 148
1960 158
1961 159
1962 132
1963 193
1964 194
1965 142
1966 111
1967 152
1968 454
1969 730
1970 703
1971 784
1972 857
1973 768
1974 624
1975 508
1976 432
1977 342
1978 286
1979 309
1980 318
1981 330
1982 367
1983 409
1984 464
1985 520
1986 520
1987 514
1988 575
1989 575
1990 657
1991 666
1992 674
1993 721
1994 756
1995 770
1996 841
1997 758
1998 824
1999 948
2000 1136
2001 1173
2002 1220
2003 1235
2004 1325
2005 1568
2006 1711
2007 1726
2008 1835
2009 1736
2010 1801
2011 1833
2012 1980
2013 1970
2014 1966
2015 1857
2016 1703
2017 1612
2018 1610
2019 1619
2020 1737
2021 1647
2022 2089
2023 1401
2024 549

Text availability

Article attribute

Article type

Publication date

Search Results

56,840 results

Results by year

Filters applied: . Clear all
Page 1
Exploration of Isoxazole-Carboxylic Acid Methyl Ester Based 2-Substituted Quinoline Derivatives as Promising Antitubercular Agents.
Kumar Sahoo S, Naiyaz Ahmad M, Kaul G, Nanduri S, Dasgupta A, Chopra S, Madhavi Yaddanapudi V. Kumar Sahoo S, et al. Chem Biodivers. 2022 Jul;19(7):e202200324. doi: 10.1002/cbdv.202200324. Epub 2022 Jun 23. Chem Biodivers. 2022. PMID: 35653161
In pursuit of potent anti-TB agents active against drug resistant tuberculosis (DR-TB), herein we report synthesis and bio-evaluation of a new series of isoxazole-carboxylic acid methyl ester based 2-substituted quinoline derivatives. ...
In pursuit of potent anti-TB agents active against drug resistant tuberculosis (DR-TB), herein we report synthesis and bio-evaluation of a n …
Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line.
Yang R, Suresh S, Velmurugan R. Yang R, et al. Appl Biochem Biotechnol. 2023 Aug;195(8):4818-4831. doi: 10.1007/s12010-022-04258-z. Epub 2022 Nov 29. Appl Biochem Biotechnol. 2023. PMID: 36445681
The aim of the present study is to synthesise an aryl ester compound from quinoline-2-carboxylic acid to evaluate its apoptotic, cell cycle blockade, and antiproliferative activity on the prostate cancer cell lines (PC3). Chromatographic and spectroscopic ana …
The aim of the present study is to synthesise an aryl ester compound from quinoline-2-carboxylic acid to evaluate its a …
Carboxylic Acid O-H Insertion Reaction of beta-Ester Diazos Enabling Synthesis of beta-Acyloxy Esters.
Li Z, Yao X, Zhang X, Mei H, Han J. Li Z, et al. J Org Chem. 2022 Nov 18;87(22):15483-15491. doi: 10.1021/acs.joc.2c02023. Epub 2022 Nov 10. J Org Chem. 2022. PMID: 36354090
Generation of non-stabilized beta-ester diazos and their applications in carboxylic acid O-H insertion reactions have been reported, which afford beta-acyloxy esters in excellent yield. ...This protocol not only realizes the reaction involving unstable …
Generation of non-stabilized beta-ester diazos and their applications in carboxylic acid O-H insertion reactions have b …
Synthesis of Carboxylic Acid and Dimer Ester Surrogates to Constrain the Abundance and Distribution of Molecular Products in alpha-Pinene and beta-Pinene Secondary Organic Aerosol.
Kenseth CM, Hafeman NJ, Huang Y, Dalleska NF, Stoltz BM, Seinfeld JH. Kenseth CM, et al. Environ Sci Technol. 2020 Oct 20;54(20):12829-12839. doi: 10.1021/acs.est.0c01566. Epub 2020 Sep 17. Environ Sci Technol. 2020. PMID: 32813970
Here, we synthesize a series of enantiopure, pinene-derived carboxylic acid and dimer ester homologues. We find that the (-)ESI efficiencies of the dimer esters are 19-36 times higher than that of cis-pinonic acid, demonstrating that the mass co …
Here, we synthesize a series of enantiopure, pinene-derived carboxylic acid and dimer ester homologues. We find that th …
Bioconversion of Phytosterols to 9-Hydroxy-3-Oxo-4,17-Pregadiene-20-Carboxylic Acid Methyl Ester by Enoyl-CoA Deficiency and Modifying Multiple Genes in Mycolicibacterium neoaurum.
Yuan C, Song S, He J, Zhang J, Liu X, Pena EL, Sun J, Shi J, Su Z, Zhang B. Yuan C, et al. Appl Environ Microbiol. 2022 Nov 22;88(22):e0130322. doi: 10.1128/aem.01303-22. Epub 2022 Oct 26. Appl Environ Microbiol. 2022. PMID: 36286498 Free PMC article.
In this study, a C22 steroid drug precursor, 9-hydroxy-3-oxo-4,17-pregadiene-20-carboxylic acid methyl ester (9-OH-PDCE), was successfully obtained from Mycolicibacterium neoaurum by 3-ketosteroid-delta(1)-dehydrogenase and enoyl-CoA hydratase ChsH deficiency …
In this study, a C22 steroid drug precursor, 9-hydroxy-3-oxo-4,17-pregadiene-20-carboxylic acid methyl ester (9-OH-PDCE …
Photocatalytic direct borylation of carboxylic acids.
Wei Q, Lee Y, Liang W, Chen X, Mu BS, Cui XY, Wu W, Bai S, Liu Z. Wei Q, et al. Nat Commun. 2022 Nov 19;13(1):7112. doi: 10.1038/s41467-022-34833-1. Nat Commun. 2022. PMID: 36402764 Free PMC article.
The preparation of high value-added boronic acids from cheap and plentiful carboxylic acids is desirable. To date, the decarboxylative borylation of carboxylic acids is generally realized through the extra step synthesized redox-active ester …
The preparation of high value-added boronic acids from cheap and plentiful carboxylic acids is desirable. To date, the …
Synthesis of Sucrose Fatty Acid Esters by Using Mixed Carboxylic-fatty Anhydrides.
Trabelsi I, Essid K, Frikha MH. Trabelsi I, et al. J Oleo Sci. 2020;69(7):693-701. doi: 10.5650/jos.ess19239. J Oleo Sci. 2020. PMID: 32612019 Free article.
Fatty acid sugar esters are non-ionic surfactant active agents with excellent performance and many uses. ...The esterification reaction of sucrose with mixed palmitic benzoic anhydride leads to a mixture of sucrose esters of palmitic acid with a good p …
Fatty acid sugar esters are non-ionic surfactant active agents with excellent performance and many uses. ...The esterification …
Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents.
Sahoo SK, Ommi O, Maddipatla S, Singh P, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM. Sahoo SK, et al. Mol Divers. 2023 Oct;27(5):2037-2052. doi: 10.1007/s11030-022-10543-0. Epub 2022 Oct 25. Mol Divers. 2023. PMID: 36282413 Free PMC article.
In our continued efforts to find potential chemotherapeutics active against drug-resistant (DR) Mycobacterium tuberculosis (Mtb), causative agent of Tuberculosis (TB) and to curb the current burdensome treatment regimen, herein we describe the synthesis and biological evaluation …
In our continued efforts to find potential chemotherapeutics active against drug-resistant (DR) Mycobacterium tuberculosis (Mtb), causative …
Nickel-Catalyzed Decarbonylative Amination of Carboxylic Acid Esters.
Malapit CA, Borrell M, Milbauer MW, Brigham CE, Sanford MS. Malapit CA, et al. J Am Chem Soc. 2020 Apr 1;142(13):5918-5923. doi: 10.1021/jacs.9b13531. Epub 2020 Mar 24. J Am Chem Soc. 2020. PMID: 32207616 Free PMC article.
The reaction of carboxylic acid derivatives with amines to form amide bonds has been the most widely used transformation in organic synthesis over the past century. Its utility is driven by the broad availability of the starting materials as well as the kinetic and …
The reaction of carboxylic acid derivatives with amines to form amide bonds has been the most widely used transformation in or …
Synthetic thioamide, benzimidazole, quinolone and derivatives with carboxylic acid and ester moieties: a strategy in the design of antituberculosis agents.
Ashfaq M, Shah SS, Najam T, Ahmad MM, Tabassum R, Rivera G. Ashfaq M, et al. Curr Med Chem. 2014 Mar;21(7):911-31. doi: 10.2174/09298673113206660302. Curr Med Chem. 2014. PMID: 24164193 Review.
Synthetic heterocyclic compounds have remarkable potential activity against diseases; thioamides, benzimidazoles, quinolones and derivatives with carboxylic acid and esters moieties have shown excellent activity against Mycobacterium tuberculosis. ...
Synthetic heterocyclic compounds have remarkable potential activity against diseases; thioamides, benzimidazoles, quinolones and derivatives …
56,840 results
You have reached the last available page of results. Please see the User Guide for more information.